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Solvonis reports positive SVN-002 bridging data; CEO outlines next steps
Proactive44d agoneutralVIDEO
Solvonis reports positive SVN-002 bridging data; CEO outlines next steps

Solvonis Therapeutics (LSE:SVNS) CEO Anthony Tennyson joined Proactive's Stephen Gunnion to discuss positive bridging pharmacokinetic data from the SVN-002 programme and what it means for the company's strategy in alcohol use disorder. Solvonis is advancing SVN-002 toward a Phase 2b trial for moderate to severe alcohol use disorder in the US, repurposing Johnson & Johnson's approved esketamine treatment Spravato via the FDA's 505(b)(2) pathway. Preclinical PK studies showed comparable exposure levels of esketamine and its metabolites via sublingual and buccal delivery compared with intranasal administration — a key step in establishing the scientific bridge the FDA requires. "We've established that esketamine delivered sublingual and buccal delivers the same exposure as esketamine delivered intranasal," Tennyson said. He pointed to a substantial commercial opportunity, with alcohol use disorder affecting around 15 million American adults, a far larger market than the treatment-resistant depression population Spravato currently serves. Tennyson said the data could support a narrower toxicology package and a faster, capital-efficient development timeline. Next steps include FDA discussions on toxicology requirements ahead of an IND application for the planned Phase 2b trial. For more Proactive interviews and market insights, visit the Proactive YouTube channel. Don't forget to like this video, subscribe to the channel and enable notifications so you never miss future content. #SolvonisTherapeutics #AnthonyTennyson #SVN002 #AlcoholUseDisorder #AUD #Biotech #Pharma #DrugDevelopment #Esketamine #Spravato #ClinicalTrials #FDA #HealthcareInnovation #LifeSciences #Investing

The 2 Factors That Will Decide Whether XLV Finally Catches the S&P 500 in 2026
24/7 Wall St.45d agoneutral
The 2 Factors That Will Decide Whether XLV Finally Catches the S&P 500 in 2026

The Health Care Select Sector SPDR ETF (NYSEARCA:XLV) is having a frustrating year. The fund sits at $149, down about 3% year-to-date while the broader market grinds higher. The good news for XLV holders: the fund has clawed back roughly 14% over the past year, and the 2026 setup looks meaningfully different from the policy ... The 2 Factors That Will Decide Whether XLV Finally Catches the S&P 500 in 2026

Own 500 Shares of Pfizer and JNJ and Here’s Your Annual Dividend Income
24/7 Wall St.45d agoneutral
Own 500 Shares of Pfizer and JNJ and Here’s Your Annual Dividend Income

Passive income is the closest thing investors have to financial gravity. It pulls in money whether you are at your desk, on a beach, or asleep, and it lands in your account no matter what the broader market did that week. Earned income depends on showing up. Dividend income depends on a board of directors ... Own 500 Shares of Pfizer and JNJ and Here’s Your Annual Dividend Income

Pharma Momentum Fuels Johnson & Johnson’s Path to Double-Digit Upside
24/7 Wall St.45d agoneutral
Pharma Momentum Fuels Johnson & Johnson’s Path to Double-Digit Upside

Our Johnson & Johnson (NYSE:JNJ) 24/7 Wall St. price target lands at $261.72, pointing to 11.28% upside from the current price of $235.18. Our recommendation is buy, and our model carries a 90% confidence level. JNJ has quietly become one of healthcare’s most reliable compounders again, with oncology firing and dividend support intact. Metric Value ... Pharma Momentum Fuels Johnson & Johnson’s Path to Double-Digit Upside

The Dividend Growth Path That Turns $500,000 Into a Six-Figure Income Stream
24/7 Wall St.45d agoneutral
The Dividend Growth Path That Turns $500,000 Into a Six-Figure Income Stream

Generating a six-figure income from a $500,000 portfolio through yield alone is largely unrealistic. Doing so would require a payout approaching 20%, a level that few investments can sustain for long. The more practical approach is to combine a reasonable starting yield with businesses that consistently increase their dividends. Over time, dividend growth and compounding ... The Dividend Growth Path That Turns $500,000 Into a Six-Figure Income Stream

This Dividend Portfolio Pays More Than Social Security and a Part-Time Job Combined
24/7 Wall St.46d agoneutral
This Dividend Portfolio Pays More Than Social Security and a Part-Time Job Combined

The average retired worker receives about $24,000 a year from Social Security. Add a modest part-time job, the kind many retirees take for supplemental income rather than career advancement, and total annual income often lands somewhere between $40,000 and $45,000 before taxes. For millions of retirees, that combination defines the retirement budget. A portfolio can ... This Dividend Portfolio Pays More Than Social Security and a Part-Time Job Combined

What a $2 Million Dividend Portfolio Actually Pays After Taxes in California
24/7 Wall St.46d agoneutral
What a $2 Million Dividend Portfolio Actually Pays After Taxes in California

A $2 million dividend portfolio may appear straightforward on paper, but the amount investors actually get to spend depends heavily on taxes. In California, the gap between gross portfolio income and after-tax cash flow can be substantial. Federal dividend tax rates, the net investment income tax, state income taxes, and the classification of each distribution ... What a $2 Million Dividend Portfolio Actually Pays After Taxes in California

Jim Cramer Says Stryker and Its Orthopedic Peers Are Facing a Real Tough Run
Insider Monkey46d agoneutral
Jim Cramer Says Stryker and Its Orthopedic Peers Are Facing a Real Tough Run

Stryker Corporation (NYSE:SYK) was among the stocks on Jim Cramer’s radar on Mad Money, as he advised investors to care about where a stock is going, not where it has been. Toward the end of the lightning round, a caller asked if the stock is a buy, sell, or hold. In response, Cramer said: See, […]

Johnson & Johnson (JNJ) Stock Draws Fresh Price Target Split On Pipeline Promise And Policy Risk
Simply Wall St.47d agoneutral
Johnson & Johnson (JNJ) Stock Draws Fresh Price Target Split On Pipeline Promise And Policy Risk

Johnson & Johnson’s model fair value sits at US$252.87 per share, with analysts keeping price targets anchored to that unchanged estimate. Recent research links those steady targets to a mix of optimism around Icotyde, Inlexzo and the broader drug pipeline, balanced against policy questions and partnership headwinds that could influence how investors think about execution risk. As you read on, you will see how these moving pieces shape the evolving Johnson & Johnson story and what to watch...

The $1 Million Retirement Mistake: Counting Income You’ll Never Get to Spend
24/7 Wall St.47d agoneutral
The $1 Million Retirement Mistake: Counting Income You’ll Never Get to Spend

A $1 million portfolio is often discussed as though the balance itself answers the retirement question. It does not. What matters is the amount of income that ultimately reaches your bank account after taxes. The yield displayed on a brokerage statement is only the starting point. Federal taxes, state taxes, and the type of income ... The $1 Million Retirement Mistake: Counting Income You’ll Never Get to Spend

The Retirement Portfolio That Forks Over a $10,000 Check Every Month
24/7 Wall St.47d agoneutral
The Retirement Portfolio That Forks Over a $10,000 Check Every Month

Ten thousand dollars a month works out to $120,000 a year, an income stream that exceeds the roughly $68,359 in per-capita disposable personal income reported by the Bureau of Economic Analysis for the first quarter of 2026. For many retirees, that level of cash flow would support a lifestyle well above basic needs. The real ... The Retirement Portfolio That Forks Over a $10,000 Check Every Month

If You Think The Market Will Ever Fall, Buy This
24/7 Wall St.47d agoneutral
If You Think The Market Will Ever Fall, Buy This

The stock market isn’t going to fall again, at least in this century. The S&P is up 8% this year. It is up 25% in the last year, and 80% over the last five. Some stocks of relatively well-known companies have doubled or better since January 1. Among the most extraordinary is the dying chip ... If You Think The Market Will Ever Fall, Buy This

Johnson & Johnson’s Erleada Cuts Risk of Cancer Spread or Death by 20%, Reuters Reports
Insider Monkey48d agobearish
Johnson & Johnson’s Erleada Cuts Risk of Cancer Spread or Death by 20%, Reuters Reports

Johnson & Johnson (NYSE:JNJ) is included among the Dividend Stock Portfolio: Top 10 Stocks to Buy According to Reddit. On May 31, Reuters reported that Johnson & Johnson (NYSE:JNJ)’s prostate cancer drug Erleada, when used alongside hormone-blocking therapy for six months before and after prostate surgery, improved the chances of eliminating cancer and lowered the […]

This $2 Million Portfolio Pays a Six-Figure Income Without Owning a Single Rental Property
24/7 Wall St.48d agoneutral
This $2 Million Portfolio Pays a Six-Figure Income Without Owning a Single Rental Property

A $2 million investment portfolio can generate a six-figure income stream without tenants, maintenance calls, property tax surprises, or vacancy risk. The arithmetic is straightforward. The challenge is deciding how much yield to pursue and understanding the trade-offs that come with it. To make a fair comparison, start with rental real estate. Many landlords aim ... This $2 Million Portfolio Pays a Six-Figure Income Without Owning a Single Rental Property

Johnson & Johnson to Invest Over $1 Billion in Florida Contact Lens Manufacturing Facility
Insider Monkey49d agoneutral
Johnson & Johnson to Invest Over $1 Billion in Florida Contact Lens Manufacturing Facility

With a net profit margin of 21.83%, Johnson & Johnson (NYSE:JNJ) is included among the 12 Most Profitable American Stocks to Buy in 2026. Johnson & Johnson (NYSE:JNJ) and its subsidiaries develop, manufacture, and sell a broad range of healthcare products, giving the company a presence across multiple areas of the healthcare industry. The company’s dividend […]

Johnson & Johnson (JNJ) Reports Phase 3 Myeloma Win For TALVEY Combination
Simply Wall St.49d agoneutral
Johnson & Johnson (JNJ) Reports Phase 3 Myeloma Win For TALVEY Combination

Johnson & Johnson (NYSE:JNJ) reported Phase 3 results for TALVEY plus DARZALEX FASPRO in relapsed or refractory multiple myeloma, showing improved outcomes versus standard regimens. The MonumenTAL-3 study is the first to show a GPRC5D bispecific antibody combination achieving these results in earlier treatment lines. Findings were published in The New England Journal of Medicine and presented at a major scientific meeting, highlighting clinical and commercial relevance. Johnson & Johnson...

Nasdaq, US stocks slide as Fed forecasts possible rate hike
Yahoo Finance Video49d agoneutralVIDEO
Nasdaq, US stocks slide as Fed forecasts possible rate hike

US stocks (^DJI, ^IXIC, ^GSPC) ended Wednesday's session in negative territory after Federal Reserve officials unanimously voted to hold interest rates at their June FOMC meeting today, while also forecasting at least one possible rate hike ahead. Yahoo Finance Markets and Data Editor Jared Blikre breaks down the trading day's market reactions to the Fed's big decision. This was Kevin Warsh's first FOMC meeting he presided over as the new chairman of the Fed.

J&J Has No Plans to Enter Obesity Drugs Market, CEO Says
Bloomberg49d agoneutralVIDEO
J&J Has No Plans to Enter Obesity Drugs Market, CEO Says

Johnson & Johnson has no plans to enter the booming obesity market, opting instead to focus on diseases such as cancer, CEO Joaquin Duato said in an interview for an upcoming episode of The David Rubenstein Show: Peer to Peer Conversations. The comments set J&J apart from many of its rivals that are trying to develop or acquire obesity medicines following blockbuster weight-loss drugs from Eli Lilly & Co. and Novo Nordisk.