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Merck’s Keytruda Faces a Patent Cliff. These New Cancer Drugs Could Take Over.
Barrons.com24d agoneutral
Merck’s Keytruda Faces a Patent Cliff. These New Cancer Drugs Could Take Over.

For many cancers now, the standard treatment is chemotherapy plus an immunotherapy such as Merck Keytruda, the best-selling drug in the world. Many think it will pair two innovations: precisely-targeted chemo drugs known as antibody-drug conjugates, or ADCs, and augmented immunotherapies in the form of bispecific antibodies. Bispecific antibodies are being tested by Bristol Myers Squibb (with its partner BioNTech ), AstraZeneca and the biotech firm Summit Therapeutics ADCs have already rung up big sales for Astra, Pfizer Gilead Sciences and Roche Holding but Merck has a strong contender in development.

What Comes After Merck’s Keytruda? The Race for the Next Standard Cancer Treatment.
Barrons.com24d agoneutral
What Comes After Merck’s Keytruda? The Race for the Next Standard Cancer Treatment.

For many cancers now, the standard treatment is chemotherapy plus an immunotherapy such as Merck Keytruda, the best-selling drug in the world. Many think it will pair two innovations: precisely-targeted chemo drugs known as antibody-drug conjugates, or ADCs, and augmented immunotherapies in the form of bispecific antibodies. Bispecific antibodies are being tested by Bristol Myers Squibb (with its partner BioNTech ), AstraZeneca and the biotech firm Summit Therapeutics ADCs have already rung up big sales for Astra, Pfizer Gilead Sciences and Roche Holding but Merck has a strong contender in development.

Merck (MRK) Wins FDA Approval For First Oral PCSK9 Cholesterol Drug
Simply Wall St.24d agobullish
Merck (MRK) Wins FDA Approval For First Oral PCSK9 Cholesterol Drug

Merck (NYSE:MRK) received FDA approval for Lipfendra (enlicitide), the first oral PCSK9 cholesterol-lowering drug. Lipfendra introduces an oral option for patients who have so far relied on injectable PCSK9 therapies. The approval expands Merck’s presence in cardiovascular medicine as key products approach patent expirations. Merck, trading around $127.5, is adding Lipfendra to its portfolio at a time when NYSE:MRK has posted a 64.8% return over the past year and 92.2% over five years. The...

Why Is PSNL Stock Up 5% After-Hours?
Stocktwits27d agoneutral
Why Is PSNL Stock Up 5% After-Hours?

Personalis has hired investment banks Centerview and TD Securities, along with law firm Cooley, to review its strategic options, according to a report in Street Insider.

Merck (MRK) Stock Sees Modest Fair Value Lift As Analysts Raise Targets
Simply Wall St.27d agoneutral
Merck (MRK) Stock Sees Modest Fair Value Lift As Analysts Raise Targets

Merck is back in focus as analysts refine their models, with bullish firms now setting price targets in a US$138 to US$155 range that sit above a refreshed fair value estimate of US$132.78 per share. These higher targets are being framed around updated earnings assumptions, views on the Q2 setup, and analysis of how Merck’s pipeline and regulatory backdrop could influence the stock’s risk and reward profile. Read on to see how to interpret these changing targets and follow the evolving Merck...

What Could Push LLY Stock Higher From Here?
Trefis27d agoneutral
What Could Push LLY Stock Higher From Here?

While the market focuses on a single class of blockbuster drugs, a different story is unfolding inside the company. Lilly’s immunology, oncology, and neuroscience medicines are quietly compounding at a blistering pace. These other therapeutic areas collectively grew by 160% last quarter, a rate that suggests a much broader growth engine is taking shape.